| Professor Cosimo De Bari
Cosimo graduated in Medicine (maxima cum laude) from the
University of Bari (Italy), where he also underwent specialist training
in Rheumatology. He then moved to Belgium, where he obtained his
PhD from the Catholic University of Leuven and was recipient of the
Rotary Young Investigator Award 2003 from the Royal Belgian Society for
In 2003 Cosimo moved to the UK in the Department of Rheumatology at
King's College London. In May 2005 he was awarded a Clinician Scientist
Fellowship from the Medical Research Council, and in December 2005 he
was appointed Clinical Senior Lecturer & Consultant Rheumatologist.
Since September 2007 Cosimo has been Professor of Translational
Medicine at the University of Aberdeen, where he heads the Regenerative
Medicine Group in the Musculoskeletal Research Programme.
Cosimo has expertise in translational stem cell research for
musculoskeletal repair, regenerative medicine and tissue
engineering. His current research interests focus on the
development of novel stem cell-based therapies for the musculoskeletal
system, mainly articular cartilage and bone; they also include the
study of the resident joint stem cells and their niches in health and
diseases such as osteoarthritis and rheumatoid arthritis.
Cosimo is a member of the Research & Training Committee of the
Osteoarthritis Research Society International (OARSI) and of the
editorial board of several journals including Regenerative Medicine and
Arthritis & Rheumatism. He serves on the Scientific Advisory
Panel of Action Medical Research and on the Fellowships Implementation
Committee of Arthritis Research UK.
5 Key Papers:
Kurth TB, Dell’Accio F, Crouch V, Augello A, Sharpe PT, De Bari C. Functional mesenchymal stem cell niches in adult mouse knee joint synovium in vivo. Arthritis Rheum. 2011; 63 (5): 1289-1300.
Zhao Z, Watt C, Karystinou A, Roelofs AJ, McCaig CD, Gibson IR, De Bari C.
Directed migration of human bone marrow mesenchymal stem cells in a
physiological direct current electric field. Eur Cell Mater. 2011;
Feng J, Mantesso A, De Bari C,
Nishiyama A, Sharpe PT. Dual origin of mesenchymal stem cells
contributing to organ growth and repair. Proc Natl Acad Sci U S A.
2011; 108 (16): 6503-6508.
MacDonald G, Augello A, De Bari C.
Role of mesenchymal stem cells in reestablishing immunologic tolerance
in autoimmune rheumatic diseases. Arthritis Rheum. 2011; 63 (9):
Nalesso G, Sherwood J, Bertrand J, Pap T, Ramachandran M, De Bari C,
Pitzalis C, Dell’Accio F. WNT-3A modulates articular chondrocyte
phenotype by activating both canonical and noncanonical pathways. J
Cell Biol. 2011; 193 (3): 551-564.