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Professor Emad M El-Omar

Professor Emad El-Omar

Professor Emad El-Omar graduated with BSc (Hons) and MB ChB from Glasgow University, Scotland, in 1988. He trained in General Internal Medicine and Gastroenterology in Glasgow and gained dual accreditation in both in 1997. In 1995 he was awarded the degree of MD with honours and Bellahouston Medal, for his work on the effect of H. pylori infection on gastric acid secretion in man. In 1997, Professor El-Omar moved to the USA spending time in the Division of Infectious Diseases at Vanderbilt University School of Medicine, Nashville, Tennessee, followed by two years at the Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, Maryland. In July 2000, Professor El-Omar took up the newly created Chair of Gastroenterology at Aberdeen University, Scotland. He is also an Honorary Consultant Physician with the Grampian University NHS Trust. Professor El-Omar is the Leader of the Immunity and Disease Programme in the Division of Applied Medicine at Aberdeen University. He is the Academic Development Coordinator for the School of Medicine and Dentistry, a role that allows him to mentor a large number of outstanding young clinician scientists and medical students. He is the Editor in Chief of the journal Gut and is the Chair of the Gastroduodenal Section of the British Society of Gastroenterology. His main research interests are in the role of microbially-induced inflammation in GI cancer and inflammatory bowel disease. His group has strong collaborations with national groups within the UK and international groups in the US, Europe, Asia and Australia.  Prof El-Omar was elected a fellow of the Royal Society of Edinburgh in 2007.

5 Key papers:

*El-Omar EM, Carrington M, Chow W-H, McColl KE, Bream J, Young HA, Herrera J, Lissowska J, Yuan C-C, Rothman N, Lanyon G, Martin M, Fraumeni JF Jr, Rabkin CS. Interleukin-1 polymorphisms associated with increased risk of gastric cancer. Nature, 2000; 404(6776): 398-402.

*El Omar EM, Rabkin CS, Gammon MD, Vaughan TL, Risch HA, Schoenberg JB, Mayne ST, Goedert JJ, Blot WJ, Fraumeni Jr JF, Chow WH. Increased risk of non cardia gastric cancer associated with pro inflammatory cytokine gene polymorphisms. Gastroenterology, 2003; 124: 1193-1201.

*Hold GL, Rabkin CS, Chow WH, Smith MG, Gammon MD, Risch HA, Vaughan TL, McColl KEL, Lissowska J, Zatonski W, Schoenberg JB, Blot WJ, Mowat NAG, Fraumeni  JFJr., El-Omar EM. A functional polymorphism of Toll-like receptor 4 gene increases risk of gastric cancer and its precursors. Gastroenterology. 2007 Mar;132(3):905-12.

*Lochhead P, Frank B, Hold GL, Rabkin CS, Ng MT, Vaughan TL, Risch HA, Gammon MD, Lissowska J, Weck MN, Raum E, Müller H, Illig T, Klopp N, Dawson A, McColl KE, Brenner H, Chow WH, El-Omar EM. Genetic variation in the prostate stem cell antigen gene and upper gastrointestinal cancer in white individuals. Gastroenterology. 2011 Feb;140(2): 435-41.

*Raju D, Hussey S, Ang M, Terebiznik MR, Gupta V, Blanke SR, Delgado A, Romero-Gallo J, Ramjeet M, Mascarenhas H, Peek RM, Correa C, Streutker C, Hold G, Kunstmann E, Yoshimori T, Silverberg M, Philpott DJ, El-Omar E, Jones NL. Vacuolating cytotoxin (VacA) and the Crohn's disease Atg16L1 variant alter autophagy and susceptibility to Helicobacter pylori infection in humans. Gastroenterology, 2012, paper in press

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Last modified: 28 January 2014  © 2007 The University of Edinburgh